Category: Science Poetry

“Swiftly, synthetic’ly,
Alice Augusta Ball
Works towards seeds of the
Chaulmoogra trees;
Efforts invested yield
Oil’s ethyl ester and 
Thus a key treatment
To combat disease.”  

The 14 April 2021 Twitter poem was another biographical tribute.  This one celebrated the chemistry achievements of Alice Augusta Ball (1892-1916), who developed the first effective medical treatment for leprosy.  

“Swiftly, synthetic’ly, / 
Alice Augusta Ball /
Works towards seeds of the / 
Chaulmoogra trees…”

Alice Ball was a gifted researcher in synthetic organic chemistry.  She completed her undergraduate work at the University of Washington and soon after earned a master’s degree from the University of Hawaii (becoming both the first Black student and the first woman to do so).  She ultimately accepted a research position at Hawaii’s Kalihi Hospital, working with surgeon Harry Hollman on a treatment for leprosy.  It was known that chaulmoogra oil, derived from “seeds of the / [c]haulmoogra trees,” was a useful treatment for this disease.  However, the oil itself had several side effects.  It couldn’t be taken orally, as it made patients ill.  Moreover, the oil couldn’t be injected without causing unwanted blistering and pain; due to its viscous nature and water-insolubility, it would clump up under the skin.        

“Efforts invested yield /
Oil’s ethyl ester and /
Thus a key treatment /
To combat disease.” 

Ball determined that if the fatty acids in the chaulmoogra oil were converted to their ethyl esters, the medication would become water-soluble: able to dissolve in water; capable of traveling through and being absorbed by the body; avoiding the terrible side effects while remaining medically active.  This was a tremendous accomplishment, revolutionizing the treatment of leprosy.    

Tragically, Ball died soon after this discovery, at the age of 24.  Moreover, another chemist, Arthur Dean, continued her work without crediting her, publishing extensively on “Dean’s method” as a leprosy treatment.  

However, years later, the credit for Ball’s work was rightfully restored, and the pertinent technique is now known as Ball’s method.  The University of Hawaii celebrated Alice Augusta Ball Day earlier in 2022.         

“Scholar and mentor,
Prof. St. Elmo Brady:
His far-reaching teaching,
Key insights, perceives.
Chemical topics and
Goals spectroscopic will,
Illuminatingly,
Landmarks achieve.”

The next Twitter biography poem, posted on 13 April 2021, celebrated St. Elmo Brady (1884-1966), who was the first Black chemist to earn a Ph.D. in the USA.  

“Scholar and mentor, /
Prof. St. Elmo Brady: /
His far-reaching teaching, /
Key insights, perceives.”

In 1916, St. Elmo Brady earned his doctorate from the University of Illinois, Urbana-Champaign (UIUC), examining how substituent effects could impact carboxylic acids.  He spent much of his subsequent career establishing chemistry departments at multiple historically Black colleges and universities (HBCUs), including Tuskegee University, Howard University, Fisk University (his undergraduate alma mater), and Tougaloo College.  He impacted countless students through his mentoring efforts in teaching and scholarship.  

“Chemical topics and /
Goals spectroscopic will, /
Illuminatingly, /
Landmarks achieve.”

These last four lines commemorate just a few specific achievements from Brady’s outstanding career, centered around the theme of achieving landmarks.  As part of his work at both Fisk University and Howard University, Brady led efforts towards construction of new academic buildings. Moreover, during his tenure at Fisk University, Brady collaborated with UIUC to develop a research institute devoted to infrared spectroscopy, a technique which identifies “chemical landmarks” (functional groups) in chemical compounds through the use of infrared light (“illuminatingly,” to use a double-dactylic word).  Finally, in 2019, the American Chemical Society celebrated Brady’s achievements with the designation of a national historic chemical landmark, at UIUC.  

After Brady’s death, chemist Samuel Massie wrote an article in The Capital Chemist in 1967 in tribute to his colleague’s life and career.  He noted: “Brady not only built buildings and departments, he built men and women.  He was never too busy to listen to the problems of a student or fellow faculty member… Although he is gone as a person, his shadow remains… Truly the story of chemistry at four institutions is the lengthened shadow of a great teacher, friend and scholar.”

“Past few months have been chaos kinetic;
Mind’s been far from rhymed verse academic.
But: still worth a try, so
Bring on NaPoWriMo,
Third attempt toward an April poetic.“

Here at the start of both a new calendar year and a new spring semester, I’ll begin revisiting the April 2021 National Poetry Writing Month poems, previously posted on Twitter.  Not all of these were science-themed, but enough were that I should be able to repeat this pattern throughout the spring.  This Twitter limerick, from 1 April 2021, merely introduces the month’s goal; it still might be useful in setting the scene for the next several weeks.    

“Past few months have been chaos kinetic; / 
Mind’s been far from rhymed verse academic.”

I wrote this limerick in the waning weeks of the 2020-21 academic year.  I was reflecting on the stress of managing day-to-day work in such an unusual time, where “chaos kinetic” was still predominating.  I had paused my Twitter poems (“rhymed verse academic”) since the end of the Fall 2020 semester.  

“But: still worth a try, so /
Bring on NaPoWriMo, /
Third attempt toward an April poetic.”   

As in April 2020, I contemplated in April 2021 the feasibility of persisting in the daily writing trend that National Poetry Writing Month (NaPoWriMo) encourages.  Thirty poems in thirty days seemed even more daunting than in the previous year.  Following successful endeavors in 2019 and 2020, the “third attempt” ultimately seemed “worth a try.”  

Part of my motivation in doing so was the possibility of generating thematic material for these subsequent essays, as that two-step process (poem first, then interpretive essay) has provided a helpful writing routine over the past two years. 

I find the poetic form of the interlocking rubaiyat particularly resonant: how the structure and word choice in one stanza informs that of the next (AABA, BBCB, CCDC, etc.).  In a similar way, by writing thirty poems in April, I can ensure that I have several themes for the following year’s blog posts, since the topics I chose for the poems inform the substance of the longer essays.  [I also note some parallels here with the structure of the Periodic Table of Elements: each essay is in the same “family” (theme) as its prompting verse and is itself a higher “number”… in terms of word count!]   

“Practical, rational
Findings: week celebrates,
Spotlighting chem work of 
National fame…
Lab-analyzingly,
Goal-synthesizingly: 
Highlight stick-to-it-ive 
Process and aims!”

The 19 October 2020 Twitter poem marked the start of National Chemistry Week 2020.

“Practical, rational /
Findings: week celebrates, /
Spotlighting chem work of /
National fame…”

The first four lines noted the general themes of National Chemistry Week, which celebrates chemistry research across the USA.  The American Chemical Society sponsors related events and campaigns, throughout late October.  Each year involves a different theme highlighting a different aspect of the discipline of chemistry.    

“Lab-analyzingly, /
Goal-synthesizingly: /
Highlight stick-to-it-ive /
Process and aims!”

The second four lines of this poem were focused on the 2020 theme for National Chemistry Week, “Sticking with Chemistry,” examining the science behind adhesives.  

Two hyphenated double-dactyl words, “lab-analyzingly” and “goal-synthesizingly,” summarized some of the main ways in which chemists complete their work.  Several types of analysis can be completed on compounds to understand their elemental composition and overall properties.  New chemical species can be synthesized in the lab, putting elements into new combinations. 

The “stick-to-it-ive” phrasing emphasized both adhesives as the subject of the 2020 celebration, specifically, and the determination with which scientists approach their goals, generally!  

This year’s week began on Monday and, for 2021, celebrates a theme related to ideas of chemical kinetics and reaction rates: “Fast or Slow, Chemistry Makes it Go.”  A new round of Twitter poems is thus in progress… which I’ll return to next year, in this space. 

“Start by observing, then
Ask informed question and
State a hypothesis;
Then test away,
Experimentally.
Findings might verify
(Or ‘back to drawing board’
Also might say…).”

I’ll return here in the autumn semester to the routine of weekly posts in which I provide additional context (“translations”) for the poems I’ve posted on Twitter in previous months. The 31 August 2020 poem summarized the scientific method in double dactylic rhythm.   

“Start by observing, then /
Ask informed question and /
State a hypothesis; /
Then test away, /
Experimentally…”

The specific details of the scientific method are listed in different ways by different sources, but major commonalities persist.  The method is driven by observations, which lead to posing a question with a tentative explanatory answer called a hypothesis.  That hypothesis can predict findings; those predictions can be tested via experiments.  (The presence of “experimentally” on a list of double-dactyl-friendly, six-syllable words prompted this particular poetic endeavor.)  

“Findings might verify /
(Or ‘back to drawing board’ /
Also might say…).”

The final few lines emphasize another aspect of the scientific method: its iterative nature.  Experiments can provide evidence (data, results, conclusions) in support of a hypothesis’s predictions (“findings might verify”), or they can provide evidence that does not support those predictions. In the latter case, a scientist would refine the hypothesis, design a new experiment, and try again: “back to [the] drawing board.”  

As a sidenote, another vocabulary term often introduced alongside the scientific method is “theory.”  A scientific theory is a explanation that has withstood many instances of rigorous testing from the scientific community; the scientific definition of “theory” is different than the everyday definition.  (One valuable metaphor I’ve heard used is that of a map: a theory connects complex information in our understanding of a particular subject into an organized format. The merit of the theory can be evaluated on the basis of the “geographical information” it provides.)

The resources linked herein provide much more detailed and informative discussions of the nature and history of the scientific method!  However, this does seem a fitting topic for the first poem “translation” of this new semester.  

Near 1920,
STEM questions aplenty.
Scientists seek for the sun in the sky
A chemical make-up.  

To do this, they take up
Their spectroscopes, which will allow them to spy
At the atomic
Scale, info re: cosmos,
Deduced from a pattern of typical lines.  
Each element will show
Fingerprint pattern, so
From scope’s results, find the source of sun’s shine.  

Opinion popular
For data ocular:
Iron composes the overhead sun.  

“Ihron?” “Yes, irhon.”
“Iht’s chlearly juhst ironh;
Whe loohked aht khey lhines frohm hour spechtroscope’s rhun!”     

Enter Payne, student,
First viewed as imprudent
For noting the excess of H in these lines.  
“Hydrogen fits
Pattern known.  It’s 
The likeliest culprit– not iron– for these spectral signs.”  

Solved, central mystery?  
Payne’s place in history
Set by the finding?  Two obvious “Yesses”?  

No!  The reception
Is cold; no exceptions.  
Some years will pass, ‘ere both are deemed as successes.  

Hydrogen’s place in the
Realms of astronomy,
Now well-established: identity main
As stars’ key constituent.  

No more diminuent 
Should be her story: Cecilia Payne.  

***

As with last week’s essay, this is a longer poem that tells one of my favorite stories from scientific history.  Cecilia Payne-Gaposchkin was an astronomer who lived from 1900-1979, and one of her stories is wonderfully told in David Bodanis’s phenomenal book E=mc², the prose of which inspired this particular poem.  Despite studying science for all of my post-college academic path, it was not until my teaching career that I encountered Payne’s name (thanks to Bodanis’s book).  

Near 1920, /
STEM questions aplenty. /
Scientists seek for the sun in the sky /
A chemical make-up.  

Cecilia Payne pursued her doctoral degree at Harvard in the early 1920s, during a time when the theory of quantum mechanics was overturning scientists’ understanding of matter and energy.  “STEM questions aplenty” were thus under investigation in various labs and universities.   One such question involved the chemical composition of the sun (which elements were present?).

To do this, they take up /
Their spectroscopes, which will allow them to spy /
At the atomic /
Scale, info re: cosmos, /
Deduced from a pattern of typical lines. /  
Each element will show /
Fingerprint pattern, so /
From scope’s results, find the source of sun’s shine.  

Several experiments around this time revolutionized scientists’ understanding of the quantum behavior of matter.  One key instrument was the spectroscope; Robert Bunsen (of “Bunsen burner” fame) and Gustav Kirchoff had shown a few decades earlier how it could be used to explore the line spectrum of a given element. 

Spectroscopes reveal the particular wavelengths (and thus energies) of light absorbed or emitted by an element; the “lines” of line spectra refer to the wavelengths in question at which they are seen.  These data in turn rely on the electronic structure of each element: its number and arrangement of electrons.   

When I teach the topic of line spectra in General Chemistry, we look at the hydrogen atom’s line spectrum in detail.  Any time a sample of hydrogen is caused to emit (release) energy, the four lines in the visible region of the electromagnetic spectrum (the colors we can see with our own eyes, rather than light that requires using a laboratory  instrument) will be at the same four wavelengths: 410 nanometers, or nm (violet), 434 nm (blue), 486 nm (indigo), and 656 nm (red).  (In teaching, I contrast this quantization with the “continuous” spectrum of white light, the ROYGBIV rainbow,  so we have a sense of why these findings would’ve been so unusual to scientists at the turn of the twentieth century.)  Each element behaves differently, so that a characteristic line spectrum becomes a fingerprint for the element in question, just as these four lines are the fingerprint for hydrogen.  

For the scientists who were interested in understanding the sun’s chemical makeup and behavior, observing the sun through a spectroscope would reveal a particular line pattern and thus the elements involved: the “source of sun’s shine.”  They were interested in the spectroscopic behavior of the elements that were causing this astronomical behavior: “at the atomic/ [s]cale, info re: cosmos.”  

Opinion popular /
For data ocular: /
Iron composes the overhead sun.  

At the time of these studies, the prevailing theory was that the sun was composed in large part of iron.  From the data that scientists could observe in the visible spectrum (“data ocular”— a bit of a stretch to serve the rhyme), they discerned lines that they attributed primarily to iron, in adherence with the theory.  

“Ihron?” “Yes, irhon.” /
“Iht’s chlearly juhst ironh; /
Whe loohked aht khey lhines frohm hour spechtroscope’s rhun!”     

These lines highlight the ingenious way that Bodanis contextualized Payne’s story, by presenting spectroscopic information as different series of letters and words and showing the reader how it would be possible to misinterpret them, if you were already sure of what you expected to see.  

In the chapter of E = mc² entitled “The Fires of the Sun,” which tells Payne’s story in the most detail, Bodanis writes: 

“An analogy can show what Payne did… If [the lines] came out, for example, as: ‘theysaidironagaien,’ you’d parse it to read ‘theysaidironagaien’ and there’d be no need to worry too much about the odd spelling of agaien…

But Payne kept an open mind.  What if it was really trying to communicate tHeysaidironagaien [?]” 

From David Bodanis’s E = mc² ; note the letters in bold in each interpretation!

I built on Bodanis’s method for showing these spectroscopic anomalies in drafting this poem.  Here, I took particular advantage of the letter h: its ability to be silent or to have only a minor effect on pronunciation,  depending on where it shows up in a word.  These lines emphasize that in this hypothetical conversation among hypothetical scientists at the time, if they were determined not to observe “h,” they could’ve plausibly denied it (the “resolved” conversation would read as: “Iron?” “Yes, iron.” / “It’s clearly just iron; / We looked at key lines from our spectroscope’s run!”).   

It does indeed take some considerable imagination to ignore the strange spellings and odd pronunciations… but that is part of this story.  As the previous post used a break in a rhyme scheme to note Perkin’s findings, the unexpected and incorrect spellings here are intended to emphasize a moment of anomaly in scientific history: something is clearly amiss, and it requires some contemplation to process and understand.

Payne carefully considered the data and proposed that, instead, the element hydrogen was responsible for these main experimental findings.

Enter Payne, student, /
First viewed as imprudent /
For noting the excess of H in these signs. /  
“Hydrogen fits /
Pattern known.  It’s / 
The likeliest culprit– not iron– for these spectral lines.”  

Over the next portion of the poem, the excess of the letter h is directly tied to the excess of the element hydrogen, represented via the chemical symbol H. 

Scientists were likewise determined not to see “H” (the chemical element H, hydrogen),  despite the evidence that Cecilia Payne presented for hydrogen’s existence in these solar spectra. 

Payne was a student at the time; it was and is particularly challenging in the structure of scientific graduate education to defy existing knowledge without the support of one’s advisor and other renowned scientists in the field.  She was “viewed as imprudent” for not adhering to the status quo, the prevailing theory of the time, in “noting the excess of [hydrogen]” in her data.

Solved, central mystery? /
Payne’s place in history /
Set by the finding?  Two obvious “Yesses”?  

The poem first optimistically queries whether Payne’s innovative findings were celebrated and her place set in scientific history: do the two specific questions of interest merit answers of “yes” ?

No!  The reception /
Is cold; no exceptions. / 
Some years will pass ere both are deemed as successes.  

As stated above, Payne’s findings were initially, frustratingly dismissed: “The reception/ [i]s cold: no exceptions.” 

In his book, Bodanis points out that Payne had to deny her key insights to complete her graduate work; he writes,

“In her own published thesis she had to insert the humiliating line: ‘The enormous abundance [of hydrogen]… is almost certainly not real.’” 

From David Bodanis’s E = mc²

It was not until years later that Payne and her insights were afforded the deserved recognition.  

Hydrogen’s place in the /
Realms of astronomy, /
Now well-established: identity main /
As stars’ key constituent. / 
No more diminuent /
Should be her story: Cecilia Payne.  

Hydrogen’s identity as a key component of stellar chemistry is now well established, as “identity main” (most abundant) for the sun and other stars.        

In 1925, Payne earned her doctoral degree in astronomy from Radcliffe College of Harvard University, as the first person to do so.  One hundred years later, Payne’s doctoral thesis is recognized as the significant insight that it was; her subsequent career was likewise inspiring and fascinating.  

However, I note that it wasn’t until I looked beyond my own STEM curriculum and textbooks that I ever heard her name.  While I can attribute that in part to my taking a chemistry-centered path, versus an astronomy-focused one, spectroscopy has still been a key topic in many of my courses, and Payne’s discovery is a compelling and dramatic illustration of the importance of spectroscopic data. 

“No more diminuent/ Should be her story”: I hope to remember this in my classrooms this autumn; rather than a “diminuent” (lessening) effect, I plan to include a focus on Payne’s inspiring discovery.

Another attempt in this month of miscellaneous metrics… and this lengthier poem could likely use more of an introduction!  I’ve written on this website about the barriers that language can throw up in learning science; this is an attempt to flip that phenomenon, to use poetic structure to help illustrate a moment in the history of chemistry. 

As I have noted when I have discussed other writers’ creative STEM-adjacent essays, I would have benefited from hearing more about the history of science and philosophy of science as a student. I am intrigued by whether there might be a way to share an accessible introduction into these interdisciplinary fields (even while I am still very much learning about both of them, myself).

This poem thus tells a story from the history of chemistry– William Perkin’s serendipitous discovery of the first synthetic (lab-made) dye– and employs the verse structure to highlight what was unusual and unexpected about it, using some of the concepts from philosopher of science Thomas Kuhn’s The Structure of Scientific Revolutions and his related essay, “The Historical Structure of Scientific Discovery,” available in the essay compilation The Essential Tension: Selected Studies in Scientific Tradition and Change.  I’ll write the poem in full first, then provide some additional context in revisiting it.    

***

Young William Perkin,
At lab bench a-workin’
On cure for malaria: task of the day.
Target synthetic
For student, mimetic
Of advisor’s goal: seek to quinine, pathway.  

Mix the reagents;
Observe mixture’s changes,
As surely, voila, target compound is made.  

Trial 1: disaster!
The lab flask is plastered 
With residue, blackened; it’s notably stained.  

Trial 2 beckons,
The chem student reckons.
Wash flask out and restart; to drawing board, back.

Ethanol rinses
The flask and evinces
Its cleanliness; solvent turns from clear to PURPLE.  

This violet in flask from cleanse collected:
A new result most wholly unexpected.
A moment of STEM’s serendipity—
Could route to hue confounding be perfected?  

Now navigating untrod territ’ry,
Investigator Perkin’s chemistry,
A route to lab-made dye: a revolution
Will rise from— NOT mistake— discovery!  

Repeat attempts yield still the mauve solution.  
For industry, route proves key substitution
For natural path to valued purple dye,
All from Will’s random act of flask elution.  

The story, decades old, still verifies
Sci Method’s start: observe, with open eyes.
Alert to novel data, self apprise.
In science, plan expected; heed surprise.  

***

Thomas Kuhn has written extensively about discovery in science and how it can change the fundamental rules by which a discipline exists, via a “paradigm shift.”  I modeled the structure of this poem using these ideas: illustrating different rules (here, rhyme schemes and poem structures, supplemented by different fonts) before and after Perkin’s unexpected discovery.  Working through these stanzas, I will aim to provide context for both the chemistry story and the poetic structure.   

***

Young William Perkin, /
At lab bench a-workin’ /
On cure for malaria: task of the day. /
Target synthetic /
For student, mimetic /
Of advisor’s goal: seek to quinine, pathway.  

William Henry Perkin worked in the lab of August Wilhelm von Hofmann as a student, in 1856; the two investigators were interested in finding a synthetic pathway to quinine, which held promise as a treatment for malaria.  The goal of the student echoed the goal of the advisor (“target synthetic / for student, mimetic / of advisor’s goal”).  

The double dactyl rhythms in these early stanzas are intentionally singsong in style, acclimating the reader to the “habit” of that familiar rhythm.  

***

Mix the reagents; /
Observe mixture’s changes, /
As surely, voila, target compound is made.  

The general plan in an organic chemistry experiment involves mixing together reagents, also called reactants, to form a product.  If a reaction works perfectly (odds are quite good that it won’t!), one would see that “surely, voila, target compound is made.”  In brief, Hofmann and Perkin knew the molecular composition (how many of what type of atom) that quinine would have, and they devised a pathway by which the component atoms could presumably be put together to get there. 

The rhythm of the double dactyl persists here, emphasizing that, for the moment, things are still going according to plan.  

***

Trial 1: disaster! /
The lab flask is plastered /
With residue, blackened; it’s notably stained.  

Synthetic endeavors take quite a bit of trouble-shooting, and it was likely not a terrible surprise to Perkin that the first go-round resulted in the formation of an unintended product, with “blackened residue” coating the inside of the flask (the glassware in which the experiment was run).  

Likewise, the poem’s rhyme scheme continues; nothing out of the ordinary is evident, as of yet.  Synthetic experiments often require multiple attempts to perfect.      

***

Trial 2 beckons, /
The chem student reckons. /
Wash flask out and restart; to drawing board, back.

After a disastrous first run, Perkin would likely have decided to simply restart the synthesis and move on to Trial 2.  In a modern lab, a chemist might use spectroscopic techniques to see what had been made instead, but without that characterization ability, Perkin presumably decided to go back to the beginning, washing out the flask and preparing for a second attempt.

Lab work can be frustrating and requires patience, but many steps are largely predictable.  The double dactyl continues apace.  

***

Ethanol rinses /
The flask and evinces /
Its cleanliness; solvent turns from clear to PURPLE.  

Perkin used ethanol to rinse out his glassware; ethanol is a common solvent that dissolves many organic compounds and is useful in cleaning ( “evinc[ing] a flask’s cleanliness”).  In doing so, he noticed that the solvent unexpectedly turned a brilliant shade of purple, as it dissolved some of the components in the residue.  This was a major shock, and the story is often cited as one of the serendipitous moments of science.  [Rather than the three-dimensional structure of quinine, which involves both aromatic (planar; flat) and aliphatic (non-planar; non-flat) regions, Perkin had synthesized a mostly aromatic, largely planar product that would ultimately be characterized as mauveine, the purplish compound that gives mauve its color.]            

In the poetic form, the rules have gone askew!  The dactyls are no more, as of the end of the stanza’s last line; trying to fit these last syllables into dactylic feet would not work.  The poetic form here aims to highlight how disquieting Perkin’s moment of discovery must have seemed.  The expected rhyme is NOT “purple”: a clear organic solvent such as ethanol would generally take on the color of what it is cleaning, and the poem established in the previous stanza that the flask was stained black.  The unexpected rhythm is intended to emphasize what Thomas Kuhn would call a “moment of anomaly” in scientific history, in a poetic context.   

***

This violet in flask from cleanse collected: /
A new result most wholly unexpected. /
A moment of STEM’s serendipity— /
Could route to hue confounding be perfected?  

What crossed Perkin’s mind, ultimately,  was the fact that, if he could repeat the steps and determine a reliable route to a purple dye, it would be commercially valuable.  Prior to his experiment, the expensive Tyrian purple dye was obtained from a natural compound obtained from the Murex snail; generating enough dye for a viable sample required thousands of snails.   If the “route to [the] hue confounding” could “be perfected,” that synthetic pathway would be tremendously valuable to the clothing industry and others who used dyes.     

In the poem, nothing is familiar compared to the starting stanzas.  Taking a step back, though, we can see that there are still regular rhymes and rhythm… if we can take the time and recalibrate, to consider how everything fits together.   We have shifted into iambic pentameter (da-DA, da-DA, da-DA; five TIMES per LINE) and into the stanza-perpetuating form (AABA, BBCB, CCDC) of the rubaiyat!  The new metric feet will likely take a few lines for the reader to adjust to, but once that adjustment is made, the poem regains a predictable form.        

***

Now navigating untrod territ’ry, /
Investigator Perkin’s chemistry, /
A route to lab-made dye: a revolution /
Will rise from— NOT mistake— discovery!  

Repeat attempts yield still the mauve solution. / 
For industry, route proves key substitution /
For natural path to valued purple dye, /
All from Will’s random act of flask elution.  

Perkin repeated the synthesis, optimized the steps, published the results, and organic chemistry was forever changed.  It is a major step when something previously available only from a scarce natural source can now be made synthetically, in a lab.  From the discovery of mauveine arose the synthetic dye industry (“key substitution / for natural path”);  from the synthetic dye industry arose the modern chemical industry, more generally.  

The rubaiyat continues with its AABA, BBCB, CCDC pattern through a few more stanzas, each line constructed via iambic pentameter.  The reader can adjust and follow the new structure of the poem to its end.  

***

The story, decades old, still verifies /
Sci Method’s start: observe, with open eyes. /
Alert to novel data, self apprise. /
In science, plan expected; heed surprise.  

Perkin’s experiment occurred more than 150 years ago, but it still provides a wonderful and dramatic story, emphasizing the crucial role of informed observation in the scientific method and echoing Louis Pasteur’s famous quote: “In the fields of observation, chance favors only the prepared mind.”  The combination of Perkin’s formal training in organic chemistry and his skills in observation let him understand the immense importance of this moment: to both “plan expected,” devising an experiment, and “heed surprise,” realizing what had happened in that moment that the solvent turned to its vivid violet color.        

This final stanza resolves the rubaiyat, with four lines’ ending in the same rhyme, giving a poetic clue that this particular story is at its end.   

***

Overall, what I’ve attempted to do here is to contrast what Kuhn would call the puzzle-solving steps of this story (using known scientific techniques to fill in known gaps in organic chemistry knowledge; here, fitting words into the structure/rhythm of double dactylic stanzas), with its moment of anomaly (the bizarre and unexpected result that requires a re-evaluation of the surrounding scientific framework; here, the interruption of the established rhyme scheme to begin a new one).  

Interestingly, the precise moment of seeing “purple” isn’t the discovery itself.  In Kuhn’s words, “discovering a new sort of phenomenon is necessarily a complex process which involves both that something is and what it is.”  More time is needed to know what’s happening and why, both for Perkin many years ago and for the reader in the moment.  What is indisputable is that the “rules” have changed; further, adapting to that unexpected observation takes some time. Those points are what I’ve aimed to illustrate through the disjointed form of this poem.