Categories
Science Poetry

By Leaps and Bounds

“Certainly, expertly,
Barbara McClintock:
Transposons deciphered
Through her watchful gaze;
Cytogeneticist,
Solving key puzzle;
Her insights are leaping
Through intricate maze.”  

The poem posted on 28 April 2020 celebrated the career and insights of Barbara McClintock, who won the Nobel Prize in Physiology or Medicine in 1983 due to her remarkable discoveries in cytogenetics.     

“Certainly, expertly, /
Barbara McClintock: /
Transposons deciphered /
Through her watchful gaze…”
Barbara McClintock (1902-1992) received the Nobel Prize “for her discovery of mobile genetic elements,” also known as transposons or jumping genes.  

A famous quote from McClintock exemplifies her “watchful gaze,” her significant observational skills: 

“No two plants are exactly alike.  They’re all different and as a consequence, you have to know that difference.  I start with the seedling and I don’t want to leave it.  I don’t feel I really know the story if I don’t watch the plant all the way along.  So I know every plant in the field.  I know them intimately.  And I find it a great pleasure to know them.” 

Barbara McClintock, quoted in “Women Who Changed Science,” via NobelPrize.org

“Cytogeneticist, /
Solving key puzzle; /
Her insights are leaping /
Through intricate maze.”  
For most of her career, McClintock worked at the Cold Spring Harbor Laboratory in New York.  She examined the overlap of cytology and genetics: the relationships between the chromosomes of corn plants (at the cellular level) and those plants’ appearances (specifically, their colors).  She discovered that the varied appearance of maize kernels at the macroscopic level could be attributed to movements of certain segments of the pertinent chromosomes at the cellular level; this was revolutionary, and it took several decades for McClintock’s work to be accepted and recognized.  

The last lines of this poem emphasize some linguistic links: first, the sounds of “maze” and “maize,” noting that McClintock’s study of corn as a model organism solved a puzzle for the larger field of genetics; second, the pairing of “leaps of insight” with the jumping genes to which McClintock devoted such significant study.